Adr have more affinity to α1 for short period of time which causes vasoconstriction and increase in BP. As it is raise systolic BP by its cardiac action but it decreases diastolic action by its peripheral action.īV contain both α1 & β2 receptors. Thus net results of this is, decrease in the peripheral resistance.Īdr can’t give in the hypotensive state. It constricts vessels of skin & mucus (mucous) membrane. Main effects of adrenaline exerted on smaller arterioles and precapillary sphincters although veins and large arteries also respond to the drug. Raised BP reflexes bradycardia due to stimulation of vagus by carotid sinus compression. Refractory period of all cells decreases. So oxygen consumption capacity and cardiac output is also increases.Ĭonduction velocity is also increases so partial AV-block overcomes. So relaxation period is also increases which shorten systole than diastole. Anaesthetics sensitize the heart to arrhythmic action of adrenaline.ĭue to Adr force of contraction increases leads to development of tension. It causes arrhythmias at high dose that raise BP markedly. It activates SA node & latent pacemakers in AV node and purkinje fibre. It increases slope of slow diastolic depolarization of SA node.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |